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Dapoxetine 30mg(same for both)
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A: Take Duralast at least 1–3 hours before anticipated sexual activity.
A: Studies tell, after three months of men taking 30 mg dose of dapoxetine took an average 2.78 minutes to ejaculate after penetration.
A: There is no permanent cure for premature ejaculation (PE), but there are treatments that can help. Some treatments include medications, counselling and techniques.
A: No. Duralast is not recommended for use in patients with heart problems (such as a heart attack or abnormal heart rhythm).
A: Duralast should be used with caution in patients with kidney diseases.
Viagra enhances blood flow to the penis, which helps in achieving and sustaining an erection. Dapoxetine helps to delay ejaculation by increasing serotonin levels in the brain, which improves control over the timing of ejaculation.
A: Consult your doctor before taking Duralast and Viagra together, as they may lower your blood pressure, especially when standing up.
A: Duralast should only be used if you are diagnosed with premature ejaculation. It is not intended for regular daily use.
A: Duralast is not recommended if you are allergic to it, men who are below 18 years or above 65 years. It is not intended for use in women. Avoid consuming alcohol as it might cause increased dizziness.
A: The mean half life of dapoxetine after a single dose was estimated using modelling as 1.3–1.5 hours.
A: Take dapoxetine exactly as instructed by your doctor. Drink a full glass of water at the same time as you take a tablet.
A: Dapoxetine is available at 2 different strengths such as 30 mg and 60 mg. The recommended starting dose for all men is 30 mg, taken as needed approximately 1 to 3 hours prior to sexual activity.
A: Dapoxetine is used for premature ejaculation (PE) in men between 18 to 64 years old.
A: Men taking a 30 mg dose of dapoxetine took an average 2.78 minutes to ejaculate after penetration, those on a 60 mg dose took 3.32 minutes.
A: Men release quickly due to premature ejaculation, nervousness of being with a new partner, anxiousness of having sex again after a long period of abstinence, lack of confidence, guilt, being overly excited or stimulated or other reasons.
swers can cause problemsAsk your doctor about PE treatment.
Reputable clinic Rest assured, couldn't be sure. Dapoxetine.Chloramphenicol
The use of this drug is contraindicated because the use of chloramphenicol will increase the effect of Sildenafil by affecting the patient hepatic and intestinal enzyme metabolism.
Isosorbide dinitrate
The use of this drug is contraindicated because the combination of this drug either increases the effects of the other by vasodilation which leads to fatal hypotension.
Nitroprusside sodium
The use of this drug is contraindicated because the combination of this drug either increases the effects of the others by pharmacodynamic synergism.
Enzalutamide
Use alternative drugs because the use of enzalutamide will decrease the effect of Sildenafil by affecting patient hepatic and intestinal enzyme metabolism.
Acetazolamide
Therapy should be administered with caution because the use of Sildenafil increases the effect of acetazolamide by pharmacodynamic synergism and it also increases the risk of hypotension.
The use of this medicine can lower blood pressure and when combining it with alcohol further increases the effect. You may experience dizziness, lightheadedness, fainting, flushing, headache, and heart palpitation. Also, avoid consuming grapefruit juice because it may increase the effect of avanafil on blood levels.
Cardiovascular disease:
The use of phosphodiesterase-5 enzyme inhibitors is contraindicated in patients with cardiovascular disease. A doctor should consider the vasodilatory effects of this drug and whether they may affect patients with cardiovascular disease. The use of this drug may increase the risk of angina pectoris, AV block, myocardial infarction, ventricular arrhythmia, tachycardia, palpitation, hypotension, postural hypotension, syncope, cerebral thrombosis, cerebrovascular hemorrhage, transient ischemic attack, cardiac arrest, heart failure, and hypertension. These events can occur during or after sexual activity.
Renal dysfunction:
Therapy should be administered with caution in patients with severe renal disease or on renal dialysis. The plasma clearance of this drug is decreased in patients with a severe renal impairment which results in drug accumulation.
Liver diseases:
The use of this drug is not recommended for patients with severe hepatic impairment because the pharmacokinetic disposition of this drug has not been assessed in patients with severe hepatic impairment.
Duralast 30mg tablet contains an active component as Dapoxetine. It is primarily used to treat premature ejaculation (PE) in men. Premature ejaculation is a common sexual health condition characterized by the inability to delay ejaculation during sexual activity, leading to distress and dissatisfaction for both the individual and their partner. Duralast 30mg tablet helps improve ejaculatory control and prolongs the time to ejaculation, allowing men to have more satisfying and prolonged sexual experiences.
Duralast 30mg tablet is contraindicated in individuals with a known hypersensitivity to the drug or its components, severe liver and kidney impairment, and those using monoamine oxidase inhibitors (MAOIs) or other SSRIs. It should also be avoided in patients with a history of mania or bipolar disorder, certain cardiovascular disorders, and epilepsy due to potential adverse effects and interactions.
This medication is not recommended for use in pediatric populations (individuals under 18) as its safety and efficacy in this age group have not been established through clinical trials. It is generally not advised for use in elderly individuals due to potential differences in efficacy, metabolism, and increased risk of side effects.
Readers’ sake for information sake;Drug-Drug Interactions:Inform the doctor if you are taking phenothiazine (thioridazine), anti-psychotic (lithium), antibiotic (linezolid, telithromycin, erythromycin, clarithromycin), an amino acid (tryptophan), pain killer (tramadol, ibuprofen, aspirin), anti-HIV (ritonavir, saquinavir, nelfinavir, atazanavir, amprenavir, fosamprenavir), anti-fungal (ketoconazole, itraconazole, fluconazole), anti-depressant (nefazodone), blood thinner (warfarin), impotent agents (sildenafil, tadalafil, vardenafil), calcium channel blocker (diltiazem, verapamil), anti-emetics (aprepitant), BPH agents and anti-migraine medicines.
Drug-Food Interactions:Do not take St. John’s wort (herbal supplement used to treat depression) while taking Dapoxetine. Avoid consuming grapefruit juice within 24 hours of taking Dapoxetine as it could lead to an increase in the level of Dapoxetine in the body.
Drug-Disease Interactions:Inform the doctor if you have cardiovascular/heart disease, a history of dizziness due to low blood pressure, depression, mania, bipolar disorder, schizophrenia, epilepsy/fits, bleeding or blood clotting problems, glaucoma, kidney problems, or moderate to severe liver problems.
Open and honest communication are key duringautions and complications.